Her study found the glymphatic clearance was mediated by a hormone called norepinephrine and happened almost exclusively during the NREM sleep phase. But it only worked when sleep was natural. Anesthesia and sleeping pills shut this process down nearly completely.

    • TypicalHog@lemm.ee
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      1 month ago

      It’s a natural hormone brain produces that signals to the body that it’s zzz time.

        • otp@sh.itjust.works
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          29 days ago

          Aside from possibly becoming a dependency, I’d imagine it doesn’t interfere with sleep quality. It’s what builds up in your body to make you sleepy/fall asleep.

          Too much might keep you groggy in the morning though.